Scrakes will never stop sprinting until they are killed. This threshold is 50% on Normal, 75% on Hard and Suicidal, and 90% on Hell on Earth.
Scrakes will only sprint when their overall health drops below a certain threshold, determined by difficulty. Damaging with on-perk weapons and then finishing it off with an off-perk weapon divides the XP and grants it to both perks.Killing with weapons other than your current perk grants the XP to the perk that weapons belongs to.The base damage value further modified by the difficulty-specific multipliers.
Scrakes have their base health value scaled accordingly to the number of players in the game. For kill reward calculations read Dosh Mechanics.